Dissecting Regulatory Interactions of RNA and Protein (Record no. 57763)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03344nam a22005295i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-3-319-07082-7 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20200421112227.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 140520s2014 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| ISBN | 9783319070827 |
| -- | 978-3-319-07082-7 |
| 082 04 - CLASSIFICATION NUMBER | |
| Call Number | 006.3 |
| 100 1# - AUTHOR NAME | |
| Author | Jens, Marvin. |
| 245 10 - TITLE STATEMENT | |
| Title | Dissecting Regulatory Interactions of RNA and Protein |
| Sub Title | Combining Computation and High-throughput Experiments in Systems Biology / |
| 300 ## - PHYSICAL DESCRIPTION | |
| Number of Pages | XVIII, 99 p. 38 illus., 19 illus. in color. |
| 490 1# - SERIES STATEMENT | |
| Series statement | Springer Theses, Recognizing Outstanding Ph.D. Research, |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Remark 2 | Introduction -- Computational analysis of PAR-CLIP data -- Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR -- Binding site occupancy with competition interactions in equilibrium -- Circular RNAs are a large class of animal RNAs with regulatory potency -- Discussion -- Methods. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | The work described in this book is an excellent example of interdisciplinary research in systems biology. It shows how concepts and approaches from the field of physics can be efficiently used to answer biological questions, and reports on a novel methodology involving creative computer-based analyses of high-throughput biological data. Many of the findings described in the book, which are the result of collaborations between the author (a theoretical scientist) and experimental biologists, and between different laboratories, have been published in high-quality peer-reviewed journals such as Molecular Cell and Nature. However, while those publications address different aspects of post-transcriptional gene regulation, this book provides readers with a complete, coherent and logical view of the research project as a whole. The introduction presents post-transcriptional gene regulation from a distinct angle, highlighting aspects of information theory and evolution, and laying the groundwork for the questions addressed in the subsequent chapters, which concern the regulation of the transcriptome as the primary functional carrier of active genetic information. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | http://dx.doi.org/10.1007/978-3-319-07082-7 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | eBooks |
| 264 #1 - | |
| -- | Cham : |
| -- | Springer International Publishing : |
| -- | Imprint: Springer, |
| -- | 2014. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
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| -- | rdacarrier |
| 347 ## - | |
| -- | text file |
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| -- | rda |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Engineering. |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Gene expression. |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Biochemistry. |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Systems biology. |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Biological systems. |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Computational intelligence. |
| 650 14 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Engineering. |
| 650 24 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Computational Intelligence. |
| 650 24 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Biological Networks, Systems Biology. |
| 650 24 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Gene Expression. |
| 650 24 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Biochemistry, general. |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| -- | 2190-5053 |
| 912 ## - | |
| -- | ZDB-2-ENG |
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