Bacterial Sensors (Record no. 85191)
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| 000 -LEADER | |
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| fixed length control field | 03632nam a22005295i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-3-031-02570-9 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240730164004.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220601s2011 sz | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| ISBN | 9783031025709 |
| -- | 978-3-031-02570-9 |
| 082 04 - CLASSIFICATION NUMBER | |
| Call Number | 510 |
| 100 1# - AUTHOR NAME | |
| Author | Meer, Jan Roelof. |
| 245 10 - TITLE STATEMENT | |
| Title | Bacterial Sensors |
| Sub Title | Synthetic Design and Application Principles / |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. 2011. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Number of Pages | XIII, 153 p. |
| 490 1# - SERIES STATEMENT | |
| Series statement | Synthesis Lectures on Synthetic Biology, |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Remark 2 | Short History of the use of Bacteria for Biosensing and Bioreporting -- Genetic Engineering Concepts -- Measuring with Bioreporters -- Epilogue. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Bacterial reporters are live, genetically engineered cells with promising application in bioanalytics. They contain genetic circuitry to produce a cellular sensing element, which detects the target compound and relays the detection to specific synthesis of so-called reporter proteins (the presence or activity of which is easy to quantify). Bioassays with bacterial reporters are a useful complement to chemical analytics because they measure biological responses rather than total chemical concentrations. Simple bacterial reporter assays may also replace more costly chemical methods as a first line sample analysis technique. Recent promising developments integrate bacterial reporter cells with microsystems to produce bacterial biosensors. This lecture presents an in-depth treatment of the synthetic biological design principles of bacterial reporters, the engineering of which started as simple recombinant DNA puzzles, but has now become a more rational approach of choosing and combining sensing, controlling and reporting DNA 'parts'. Several examples of existing bacterial reporter designs and their genetic circuitry will be illustrated. Besides the design principles, the lecture also focuses on the application principles of bacterial reporter assays. A variety of assay formats will be illustrated, and principles of quantification will be dealt with. In addition to this discussion, substantial reference material is supplied in various Annexes. Table of Contents: Short History of the use of Bacteria for Biosensing and Bioreporting / Genetic Engineering Concepts / Measuring with Bioreporters / Epilogue. |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| General subdivision | Technique. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | https://doi.org/10.1007/978-3-031-02570-9 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | eBooks |
| 264 #1 - | |
| -- | Cham : |
| -- | Springer International Publishing : |
| -- | Imprint: Springer, |
| -- | 2011. |
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| -- | text |
| -- | txt |
| -- | rdacontent |
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| -- | computer |
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| -- | rdamedia |
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| -- | online resource |
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| -- | rdacarrier |
| 347 ## - | |
| -- | text file |
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| -- | rda |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Mathematics. |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Engineering. |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Biotechnology. |
| 650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Biology |
| 650 14 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Mathematics. |
| 650 24 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Technology and Engineering. |
| 650 24 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Biotechnology. |
| 650 24 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
| -- | Biological Techniques. |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| -- | 2151-0016 |
| 912 ## - | |
| -- | ZDB-2-SXSC |
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