Chapter 1 Introducing Chronic Graft Failure / Harold C. Yang -- chapter 2 Chronic Allograft Failure: Past, Present and Future / Basit Javaid andJohn D. Scandling -- chapter 3 Solid Organ Transplantation?An Overview / Roy D. Bloom -- chapter 4 Analyzing Graft Failure in the Scientific Registry of Transplant Recipients: The Sources and Nature of the Data Available / DavidM. Dickinson, Gregory N Levine, -- chapter 5 The Immunology of Chronic Allograft Injury / Raphael Ihuillier -- chapter 6 Ischemia-Reperfusion Injury: Pathophysiology and Clinical Approach / Maria Teresa Gandolfo -- chapter 7 Heat Shock Protein 47 in Chronic Allograft Nephropathy / Takashi Taguchi -- chapter 8 Dendritic Cell-Based Approaches to Organ Transplantation -- chapter 9 Cardiac Allograft Vasculopathy. Jignesh K. Patel and Jon A. Kobashigawa -- chapter 10 The Pathology of Heart Allograft Rejection / Jon Carthy -- chapter 11 Experimental Gene Therapy of Heart Transplantation / Giuseppe Vassalli -- chapter 12 The Basic Science of Lung Allograft Failure / Trudie Goers -- chapter 13 The Role for Cytokine Responses in the Pathogenesis of Lung Allograft Dysfunction -- chapter 14 Diagnosis of Chronic Graft Failure after Lung Transplantation -- chapter 15 Treatment of Chronic Graft Failure after Lung Transplantation -- chapter 16 Liver Transplantation?An Overview / Tiffany E. Kaiser, E. Steve Woodle and Guy W.N eff -- chapter 17 Hepatic Allograft Loss: Pathogenesis, Diagnosis and Management -- chapter 18 Chronic Allograft Dysfunction?Liver / Susan Lemer -- chapter 19 Liver Graft Loss Due to Vascular Complications. / Barbara Stange -- chapter 20 Late Allograft Failure: Liver / Jeffrey S. Crippin -- chapter 21 Liver Allograft Failure Due to Recurrent Disease?Pathology -- chapter 22 Chronic Allograft Enteropathy / Gonzalo P. Rodriguez-Laiz -- chapter 23 Renal Allograft Survival: Epidemiologic Considerations / Titte R. Srinivas andHerwig-UlfMeier'Kriesche -- chapter 24 Predictive Parameters of Renal Graft Failure / Paola Romagnani -- chapter 25 Clinico-Pathological Correlations o f Chronic Allograft Nephropathy -- chapter 26 Recurrent Glomerular Disease in the Allograft: Risk Factors and Management -- chapter 27 Pathology o f Kidney Allograft Dysfunction / Bela Ivanyi -- chapter 28 Islet of Langerhans -- Cellular Structure and Physiology / Amanda Jabin Gustafsson andMd. Shahidul Islam -- chapter 29 * Islet Transplantation / Breay W. Paty and A.M. James Shapiro -- chapter 30 Metabolic Indicators of Islet Graft Dysfunction / RaquelN. Faradji, Kathy Monroy, Misha Denham, -- chapter 31 Pancreas and Islet Allograft Failure / Patrick G. Dean -- chapter 32 Chronic Pancreas Allograft Failure / Elizabeth K. Gross and Rainer W.G. Gruessner -- chapter 33 Pathological Aspects of Pancreas Allograft Failure -- chapter 34 The Graft: Emerging Viruses in Transplantation -- chapter 35 Cytomegalovirus and Allograft Failure after Solid Organ Transplantation -- chapter 36 Hepatitis C Virus Infection as a Risk Factor for Graft Loss after Renal Transplantation -- chapter 37 Polyomavirus Type BK-Associated Nephropathy and Renal Allograft Graft Loss: Natural History, Patho-Physiology, Diagnosis and Management -- chapter 38 Polyomavirus Allograft Nephropathy: ClinicO'Pathological Correlations / Volker Nickeleit -- chapter 39 Pharmacotherapeutic Options in Solid Organ Transplantation / Jennifer Trofe.

This book addresses one of the largest unmet needs in transplantation, the need to reduce late allograft loss. In the current era, it is reasonable to expect that most allografts will serve their recipients through their life span and death with preserved graft function the ultimate goal for all transplant recipients. However, long term allograft survival has not paralleled improvements made in short term survival. Each year a percentage of the existing organ transplant patients will lose their grafts. The problem of late allograft failure is due in part to pathogenic processes, to drug management, and to transplant patient care delivery. This book pulls together the science in this area and serves as a resource and as a catalyst for further research. The book has been divided into sections covering the entirety of chronic allograft loss from basic science consideration to clinical implications. The goal of this book is to provide the reader with an overview of long term problems in solid organ transplantation. This overview not only includes the diagnosis of immunologic and non-immunologic causes of chronic graft loss but current management as well as novel therapies for future application. This book will make a useful contribution to the literature.

OCLC-licensed vendor bibliographic record.