000			03070nam a22005415i 4500
001			978-3-319-13266-2
003			DE-He213
005			20200421112547.0
007			cr nn 008mamaa
008			141205s2015 gw | s |||| 0|eng d
020			_a9783319132662 _9978-3-319-13266-2
024	7		_a10.1007/978-3-319-13266-2 _2doi
050		4	_aR856-857
072		7	_aMQW _2bicssc
072		7	_aTEC009000 _2bisacsh
082	0	4	_a610.28 _223
245	1	2	_aA Tissue Regeneration Approach to Bone and Cartilage Repair _h[electronic resource] / _cedited by Hala Zreiqat, Colin R. Dunstan, Vicki Rosen.
264		1	_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2015.
300			_aVI, 254 p. 48 illus. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aMechanical Engineering Series, _x0941-5122
520			_aReviewing exhaustively the current state of the art of tissue engineering strategies for regenerating bones and joints through the use of biomaterials, growth factors and stem cells, along with an investigation of the interactions between biomaterials, bone cells, growth factors and added stem cells and how together skeletal tissues can be optimised, this book serves to highlight the importance of biomaterials composition, surface topography, architectural and mechanical properties in providing support for tissue regeneration. Maximizing reader insights into the importance of the interplay of these attributes with bone cells (osteoblasts, osteocytes and osteoclasts) and cartilage cells (chondrocytes), this book also provides a detailed reference as to how key signalling pathways are activated. The contribution of growth factors to drive tissue regeneration and stem cell recruitment is discussed along with a review the potential and challenges of adult or embryonic mesenchymal stem cells to further enhance the formation of new bone and cartilage tissues. This book serves to demonstrate the interconnectedness of biomaterials, bone/cartilage cells, growth factors and stem cells in determining the regenerative process and thus the clinical outcome.
650		0	_aEngineering.
650		0	_aMedical microbiology.
650		0	_aBiophysics.
650		0	_aBiological physics.
650		0	_aBiomedical engineering.
650		0	_aBiomaterials.
650	1	4	_aEngineering.
650	2	4	_aBiomedical Engineering.
650	2	4	_aBiomaterials.
650	2	4	_aMedical Microbiology.
650	2	4	_aBiophysics and Biological Physics.
700	1		_aZreiqat, Hala. _eeditor.
700	1		_aDunstan, Colin R. _eeditor.
700	1		_aRosen, Vicki. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783319132655
830		0	_aMechanical Engineering Series, _x0941-5122
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-319-13266-2
912			_aZDB-2-ENG
942			_cEBK
999			_c58636 _d58636