000 07406nam a2200589 i 4500
001 8371515
003 IEEE
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006 m o d
007 cr |n|||||||||
008 190826s2018 nju ob 001 eng d
010 _z 2017050886 (print)
015 _zGBB916976 (print)
016 _z018847862 (print)
020 _a1119218357
020 _a1119218349
020 _z9781119218357
_qpdf
020 _a9781119218333
_qelectronic book
020 _z9781119218340
_qePub
020 _a1119218330
020 _z9781119218326
_qhardback
035 _a(CaBNVSL)mat08371515
040 _aCaBNVSL
_beng
_erda
_cCaBNVSL
_dCaBNVSL
050 0 0 _aRA856.4
_b.Y853 2018eb
082 0 0 _a610.28/4
_223
100 1 _aYu, Hao,
_d1976-
_eauthor.
_929365
245 1 0 _aCMOS integrated lab-on-a-chip system for personalized biomedical diagnosis /
_cHao Yu, Southern University of Science and Technology, China, Mei Yan, Consultant, China, Xiwei Huang, Hangzhou Dianzi University, China.
264 1 _aHoboken, New Jersey :
_bWiley / IEEE Press,
_c2018.
264 2 _a[Piscataqay, New Jersey] :
_bIEEE Xplore,
_c[2018]
300 _a1 PDF.
336 _atext
_2rdacontent
337 _aelectronic
_2isbdmedia
338 _aonline resource
_2rdacarrier
504 _aIncludes bibliographical references and index.
505 0 _aIntro; Title Page; Copyright Page; Contents; Preface; Chapter 1 Introduction; 1.1 Personalized Biomedical Diagnosis; 1.1.1 Personalized Diagnosis; 1.1.2 Conventional Biomedical Diagnostic Instruments; 1.1.2.1 Optical Microscope; 1.1.2.2 Flow Cytometer; 1.1.2.3 DNA Sequencer; 1.2 CMOS Sensor-based Lab-on-a-Chip for System Miniaturization; 1.2.1 CMOS Sensor-based Lab-on-a-Chip; 1.2.2 CMOS Sensor; 1.2.2.1 CMOS Process Fundamentals; 1.2.2.2 CMOS Sensor Technology; 1.2.2.3 Multimodal CMOS Sensor; 1.2.3 Microfluidics; 1.2.3.1 Microfluidic Fundamentals; 1.2.3.2 Microfluidics Fabrication.
505 8 _a1.3 Objectives and Organization of this Book1.3.1 Objectives; 1.3.2 Organization; References; Chapter 2 CMOS Sensor Design; 2.1 Top Architecture; 2.2 Noise Overview; 2.2.1 Thermal Noise; 2.2.2 Flicker Noise; 2.2.3 Shot Noise; 2.2.4 MOSFET Noise Model; 2.3 Pixel Readout Circuit; 2.3.1 Source Follower; 2.3.2 Sub-threshold Gm Integrator; 2.3.3 CTIA; 2.4 Column Amplifier; 2.5 Column ADC; 2.5.1 Single-Slope ADC; 2.5.2 Sigma-Delta ADC; 2.6 Correlated Sampling; 2.6.1 Correlated Double Sampling; 2.6.2 Correlated Multiple Sampling; 2.7 Timing Control; 2.7.1 Row Timing Control.
505 8 _a2.7.2 Column Timing Control2.8 LVDS Interface; References; Chapter 3 CMOS Impedance Sensor; 3.1 Introduction; 3.2 CMOS Impedance Pixel; 3.3 Readout Circuit; 3.4 A 96 x 96 Electronic Impedance Sensing System; 3.4.1 Top Architecture; 3.4.2 System Implementation; 3.4.2.1 System Setup; 3.4.2.2 Sample Preparation; 3.4.3 Results; 3.4.3.1 Data Fitting for Single Cell Impedance Measurement; 3.4.3.2 Cell and Electrode Impedance Analysis; 3.4.3.3 EIS for Single-Cell Impedance Enumeration; References; Chapter 4 CMOS Terahertz Sensor; 4.1 Introduction; 4.2 CMOS THz Pixel.
505 8 _a4.2.1 Differential TL-SRR Resonator Design4.2.1.1 Stacked SRR Layout; 4.2.1.2 Comparison with Single-ended TL-SRR Resonator; 4.2.1.3 Comparison with Standing-Wave Resonator; 4.2.2 Differential TL-CSRR Resonator Design; 4.3 Readout Circuit; 4.3.1 Super-regenerative Amplification; 4.3.1.1 Equivalent Circuit of SRA; 4.3.1.2 Frequency Response of SRA; 4.3.1.3 Sensitivity of SRA; 4.3.2 Super-regenerative Receivers; 4.3.2.1 Quench-controlled Oscillation; 4.3.2.2 SRX Design by TL-CSRR; 4.3.2.3 SRX Design by TL-SRR; 4.4 A 135 GHz Imager; 4.4.1 135 GHz DTL-SRR-based Receiver.
505 8 _a4.4.2 System Implementation4.4.3 Results; 4.5 Plasmonic Sensor for Circulating Tumor Cell Detection; 4.5.1 Introduction of CTC Detection; 4.5.2 SRR-based Oscillator for CTC Detection; 4.5.3 Sensitivity of SRR-based Oscillator; References; Chapter 5 CMOS Ultrasound Sensor; 5.1 Introduction; 5.2 CMUT Pixel; 5.3 Readout Circuit; 5.4 A 320 × 320 CMUT-based Ultrasound Imaging System; 5.4.1 Top Architecture; 5.4.2 System Implementation; 5.4.2.1 Process Selection; 5.4.2.2 High Voltage Pulser; 5.4.2.3 Low-Noise Preamplifier and High Voltage Switch; 5.4.3 Results; 5.4.3.1 Simulation Results.
506 _aRestricted to subscribers or individual electronic text purchasers.
520 _aA thorough examination of lab-on-a-chip circuit-level operations to improve system performance A rapidly aging population demands rapid, cost-effective, flexible, personalized diagnostics. Existing systems tend to fall short in one or more capacities, making the development of alternatives a priority. CMOS Integrated Lab-on-a-Chip System for Personalized Biomedical Diagnosis provides insight toward the solution, with a comprehensive, multidisciplinary reference to the next wave of personalized medicine technology. A standard complementary metal oxide semiconductor (CMOS) fabrication technology allows mass-production of large-array, miniaturized CMOS-integrated sensors from multi-modal domains with smart on-chip processing capability. This book provides an in-depth examination of the design and mechanics considerations that make this technology a promising platform for microfluidics, micro-electro-mechanical systems, electronics, and electromagnetics. From CMOS fundamentals to end-user applications, all aspects of CMOS sensors are covered, with frequent diagrams and illustrations that clarify complex structures and processes. Detailed yet concise, and designed to help students and engineers develop smaller, cheaper, smarter lab-on-a-chip systems, this invaluable reference: -Provides clarity and insight on the design of lab-on-a-chip personalized biomedical sensors and systems -Features concise analyses of the integration of microfluidics and micro-electro-mechanical systems -Highlights the use of compressive sensing, super-resolution, and machine learning through the use of smart SoC processing -Discusses recent advances in complementary metal oxide semiconductor-integrated lab-on-a-chip systems -Includes guidance on DNA sequencing and cell counting applications using dual-mode chemical/optical and energy harvesting sensors The conventional reliance on the microscope, flow cytometry, and DNA sequencing leaves diagnosticians tied to bulky, expensive equipment with a central problem of scale. Lab-on-a-chip technology eliminates these constraints while improving accuracy and flexibility, ushering in a new era of medicine. This book is an essential reference for students, researchers, and engineers working in diagnostic circuitry and microsystems.'
530 _aAlso available in print.
538 _aMode of access: World Wide Web
588 _aDescription based on PDF viewed 08/26/2019.
650 0 _aMedical instruments and apparatus
_xResearch.
_96052
650 0 _aMetal oxide semiconductors, Complementary.
_93260
655 4 _aElectronic books.
_93294
710 2 _aIEEE Xplore (Online Service),
_edistributor.
_929366
776 0 8 _iPrint version:
_aYu, Hao 1976-
_tCMOS integrated lab-on-a-chip system for personalized biomedical diagnosis.
_dHoboken, NJ : Wiley, 2018
_z9781119218326
_w(DLC) 2017049248
856 4 2 _3Abstract with links to resource
_uhttps://ieeexplore.ieee.org/xpl/bkabstractplus.jsp?bkn=8371515
942 _cEBK
999 _c74567
_d74567