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001 978-3-030-52355-8
003 DE-He213
005 20220801215804.0
007 cr nn 008mamaa
008 200925s2020 sz | s |||| 0|eng d
020 _a9783030523558
_9978-3-030-52355-8
024 7 _a10.1007/978-3-030-52355-8
_2doi
050 4 _aTK7867-7867.5
072 7 _aTJFC
_2bicssc
072 7 _aTEC008010
_2bisacsh
072 7 _aTJFC
_2thema
082 0 4 _a621.3815
_223
100 1 _aBaig, Hasan.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_946466
245 1 0 _aGenetic Design Automation
_h[electronic resource] :
_bA Practical Approach for the Analysis, Verification and Synthesis of Genetic Logic Circuits /
_cby Hasan Baig, Jan Madsen.
250 _a1st ed. 2020.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2020.
300 _aXVI, 164 p. 158 illus., 148 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aIntroduction -- Fundamentals of Molecular Biology and Genetic Circuits -- Dynamic Virtual Analyzer and Simulator -- Genetic Circuits Timing Analysis -- Genetic Circuits Logic Analysis -- Technology Mapping of Genetic Circuits -- Parameter Estimation and Sensitivity Analysis -- Learn to program rapidly with graphical programming -- Project 1 – Stochastic Simulation -- Project 2 – Parsing SBML -- Project 3 – Circuit generation with SBOL.
520 _aThis textbook introduces readers to the recent advances in the emerging field of genetic design automation (GDA). Starting with an introduction and the basic concepts of molecular biology, the authors provide an overview of various genetic design automation tools. The authors then present the DVASim tool (Dynamic Virtual Analyzer and Simulator) which is used for the analysis and verification of genetic logic circuits. This includes methods and algorithms for the timing and threshold value analyses of genetic logic circuits. Next, the book presents the GeneTech tool (A technology mapping tool for genetic circuits) and the methods developed for optimization, synthesis, and technology mapping of genetic circuits. Chapters are followed by exercises which give readers hands-on practice with the tools presented. The concepts and algorithms are thoroughly described, enabling readers to improve the tools or use them as a starting point to develop new tools. Both DVASim and GeneTech are available from the developer’s website, free of charge. This book is intended for a multidisciplinary audience of computer scientists, engineers and biologists. It provides enough background knowledge for computer scientists and engineers, who usually do not have any background in biology but are interested to get involved in this domain. This book not only presents an accessible basic introduction to molecular biology, it also includes software tools which allow users to perform laboratory experiments in a virtual in-silico environment. This helps newbies to get a quick start in understanding and developing genetic design automation tools. The third part of this book is particular useful for biologists who usually find it difficult to grasp programming and are reluctant to developing computer software. They are introduced to the graphical programming language, LabVIEW, from which they can start developing computer programs rapidly. Readers are further provided with small projects which will help them to start developing GDA tools.
650 0 _aElectronic circuits.
_919581
650 0 _aBiomedical engineering.
_93292
650 0 _aBioinformatics.
_99561
650 1 4 _aElectronic Circuits and Systems.
_946467
650 2 4 _aBiomedical Engineering and Bioengineering.
_931842
650 2 4 _aBioinformatics.
_99561
700 1 _aMadsen, Jan.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_946468
710 2 _aSpringerLink (Online service)
_946469
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783030523541
776 0 8 _iPrinted edition:
_z9783030523565
776 0 8 _iPrinted edition:
_z9783030523572
856 4 0 _uhttps://doi.org/10.1007/978-3-030-52355-8
912 _aZDB-2-ENG
912 _aZDB-2-SXE
942 _cEBK
999 _c77865
_d77865