000 04209nam a22006015i 4500
001 978-3-319-41475-1
003 DE-He213
005 20220801221134.0
007 cr nn 008mamaa
008 160914s2017 sz | s |||| 0|eng d
020 _a9783319414751
_9978-3-319-41475-1
024 7 _a10.1007/978-3-319-41475-1
_2doi
050 4 _aR856-857
072 7 _aMQW
_2bicssc
072 7 _aTEC059000
_2bisacsh
072 7 _aMQW
_2thema
082 0 4 _a610.28
_223
245 1 0 _aBiomechanics: Trends in Modeling and Simulation
_h[electronic resource] /
_cedited by Gerhard A. Holzapfel, Ray W. Ogden.
250 _a1st ed. 2017.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2017.
300 _aIX, 316 p. 129 illus., 63 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aStudies in Mechanobiology, Tissue Engineering and Biomaterials,
_x1868-2014 ;
_v20
505 0 _aMixture theory for modeling biological tissues: illustrations from articular cartilage -- A bio-chemo-mechanical model for cell contractility, adhesion, signaling and stress-fiber remodeling -- Nonlinear continuum mechanics and modeling the elasticity of soft biological tissues with a focus on artery wall -- Microstructure and mechanics of human aortas in health and disease -- Arterial and atherosclerotic plaque biomechanics with application to stent angiopasty modeling -- Biomechanics of myocardial ischemia and infarction.
520 _aThe book presents a state-of-the-art overview of biomechanical and mechanobiological modeling and simulation of soft biological tissues. Seven well-known scientists working in that particular field discuss topics such as biomolecules, networks and cells as well as failure, multi-scale, agent-based, bio-chemo-mechanical and finite element models appropriate for computational analysis. Applications include arteries, the heart, vascular stents and valve implants as well as adipose, brain, collagenous and engineered tissues. The mechanics of the whole cell and sub-cellular components as well as the extracellular matrix structure and mechanotransduction are described. In particular, the formation and remodeling of stress fibers, cytoskeletal contractility, cell adhesion and the mechanical regulation of fibroblast migration in healing myocardial infarcts are discussed. The essential ingredients of continuum mechanics are provided. Constitutive models of fiber-reinforced materials with an emphasis on arterial walls and the myocardium are discussed and the important influence of residual stresses on material response emphasized. The mechanics and function of the heart, the brain and adipose tissues are discussed as well. Particular attention is focused on microstructural and multi-scale modeling, finite element implementation and simulation of cells and tissues.
650 0 _aBiomedical engineering.
_93292
650 0 _aMathematical models.
_94632
650 0 _aMechanics, Applied.
_93253
650 0 _aBiomaterials.
_916365
650 0 _aBiophysics.
_94093
650 1 4 _aBiomedical Engineering and Bioengineering.
_931842
650 2 4 _aMathematical Modeling and Industrial Mathematics.
_933097
650 2 4 _aEngineering Mechanics.
_931830
650 2 4 _aBiomaterials.
_916365
650 2 4 _aBiophysics.
_94093
700 1 _aHolzapfel, Gerhard A.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_954317
700 1 _aOgden, Ray W.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_954318
710 2 _aSpringerLink (Online service)
_954319
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783319414737
776 0 8 _iPrinted edition:
_z9783319414744
776 0 8 _iPrinted edition:
_z9783319823645
830 0 _aStudies in Mechanobiology, Tissue Engineering and Biomaterials,
_x1868-2014 ;
_v20
_954320
856 4 0 _uhttps://doi.org/10.1007/978-3-319-41475-1
912 _aZDB-2-ENG
912 _aZDB-2-SXE
942 _cEBK
999 _c79332
_d79332