| 000 | 03837nam a22005655i 4500 | ||
|---|---|---|---|
| 001 | 978-3-319-67609-8 | ||
| 003 | DE-He213 | ||
| 005 | 20220801221306.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 171030s2018 sz | s |||| 0|eng d | ||
| 020 |
_a9783319676098 _9978-3-319-67609-8 |
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| 024 | 7 |
_a10.1007/978-3-319-67609-8 _2doi |
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| 050 | 4 | _aR856-857 | |
| 072 | 7 |
_aMQW _2bicssc |
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| 072 | 7 |
_aTEC059000 _2bisacsh |
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| 072 | 7 |
_aMQW _2thema |
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| 082 | 0 | 4 |
_a610.28 _223 |
| 100 | 1 |
_aManisekaran, Ravichandran. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut _955185 |
|
| 245 | 1 | 0 |
_aDesign and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics _h[electronic resource] / _cby Ravichandran Manisekaran. |
| 250 | _a1st ed. 2018. | ||
| 264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2018. |
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| 300 |
_aXL, 168 p. 91 illus., 84 illus. in color. _bonline resource. |
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| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 347 |
_atext file _bPDF _2rda |
||
| 490 | 1 |
_aSpringer Theses, Recognizing Outstanding Ph.D. Research, _x2190-5061 |
|
| 505 | 0 | _aIntroduction to Nanomedicine and Cancer Therapy -- Literature Survey on Magnetic, Gold and Core-Shell Nanoparticles -- Characterization Techniques, Cell Cultivation and Experimental Setup -- Designing a Nanocargo with Fe3O4@Au: A Tri-pronged Mechanism for MR Imaging, Synaphic Drug-delivery and Apoptosis Induction in Cancer Cells -- Multiple Iterative Seeding of Surface Plasmon Enhanced Cobalt-Iron Oxide Nanokernels for Cancer Theranostics -- Nano-flotillas MnFe2O4@Au Core-shell Nanoparticles: An Efficient MRI Contrast Agent, Magneto-hyperthermal and Drug-delivery Armada for Cancer -- Concluding Remarks and Future Prospects. | |
| 520 | _aThis thesis documents the development of a multifunctional nanoparticle system to enhance the chemotherapeutic efficiency of anti-cancer drugs, and contributes to research that helps decrease the side-effects in cancer patients while simultaneously increasing their survival rates. The work begins with an introduction to nanomedicine and cancer therapy, and contains a literature review on magnetic, gold, and core-shell nanoparticles. It also covers synthesis techniques, properties, various surface modifications, and the importance of magnetic and gold nanoparticles. The author dedicates a chapter to characterization techniques, experimental setup, and cell cultivation techniques for in-vitro studies. Further chapters describe the background, characterizations, and applications of multifunctional magnetite coated gold core-shell nanoparticles, and the doping of cobalt to magnetite and manganese to magnetite nanoparticles. The important highlight of this research was the control of the size, shape, composition, and surface chemistry of nanoparticles. | ||
| 650 | 0 |
_aBiomedical engineering. _93292 |
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| 650 | 0 |
_aNanotechnology. _94707 |
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| 650 | 0 |
_aCancer. _915213 |
|
| 650 | 0 |
_aNanoscience. _910727 |
|
| 650 | 1 | 4 |
_aBiomedical Engineering and Bioengineering. _931842 |
| 650 | 2 | 4 |
_aNanotechnology. _94707 |
| 650 | 2 | 4 |
_aCancer Biology. _936669 |
| 650 | 2 | 4 |
_aNanophysics. _932302 |
| 710 | 2 |
_aSpringerLink (Online service) _955186 |
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| 773 | 0 | _tSpringer Nature eBook | |
| 776 | 0 | 8 |
_iPrinted edition: _z9783319676081 |
| 776 | 0 | 8 |
_iPrinted edition: _z9783319676104 |
| 776 | 0 | 8 |
_iPrinted edition: _z9783319884578 |
| 830 | 0 |
_aSpringer Theses, Recognizing Outstanding Ph.D. Research, _x2190-5061 _955187 |
|
| 856 | 4 | 0 | _uhttps://doi.org/10.1007/978-3-319-67609-8 |
| 912 | _aZDB-2-ENG | ||
| 912 | _aZDB-2-SXE | ||
| 942 | _cEBK | ||
| 999 |
_c79504 _d79504 |
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