000			05211cam a2200589 a 4500
001			on1190852496
003			OCoLC
005			20230516165904.0
006			m o d
007			cr |n|||||||||
008			200828s2020 ne o 001 0 eng d
040			_aYDX _beng _epn _cYDX _dOPELS _dEBLCP _dUKAHL _dUKMGB _dOCLCF _dOCLCO _dOCLCQ _dOCLCO _dK6U _dN$T _dOCLCQ
015			_aGBC087817 _2bnb
016	7		_a019848836 _2Uk
020			_a9780128181294 _q(electronic bk.)
020			_a012818129X _q(electronic bk.)
020			_z0128181281
020			_z9780128181287
035			_a(OCoLC)1190852496
050		4	_aR857.M3
082	0	4	_a610.28 _223
245	0	0	_aBiomaterials for 3D tumor modeling / _cedited by Subhas C. Kundu and Rui L. Reis.
260			_aAmsterdam, Netherlands : _bElsevier, _c2020.
300			_a1 online resource
336			_atext _btxt _2rdacontent
336			_astill image _bsti _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
490	0		_aMaterials today
500			_aIncludes index.
505	0		_aFront Cover -- Biomaterials for 3D Tumor Modeling -- Copyright Page -- Contents -- List of Contributors -- Preface -- I. Engineering biomaterials for 3D cancer modelling -- 1 Trends in biomaterials for three-dimensional cancer modeling -- Abbreviations -- 1.1 A historical introduction -- 1.1.1 In vitro and in vivo models: an overview -- 1.1.2 A paradigm shift -- 1.1.3 Three-dimensional biomaterials for cancer modeling -- 1.1.4 From the lab to the clinic -- 1.2 The three-dimensional tumor microenvironment -- 1.2.1 The tumor and its three-dimensional environment: a synergistic interaction
505	8		_a1.2.2 Biomaterials as a model of the tumor niche -- 1.2.2.1 Scaffold-based biomaterials -- 1.2.2.2 Matrix-based -- 1.2.2.3 Microcarrier-based -- 1.2.2.4 Scaffold-free: tumor spheroids -- 1.2.2.5 Microstructured surfaces -- 1.3 Engineering the native tumor microenvironment using custom-designed three-dimensional biomaterials -- 1.3.1 Tissue engineering approaches -- 1.3.1.1 Freeze-drying -- 1.3.1.2 Photopolymerization -- 1.3.1.3 Three-dimensional bioprinting -- 1.3.2 Nanotechnology approaches -- 1.3.2.1 Molding -- 1.3.2.2 Printing -- 1.3.2.2.1 (Two-dimensional) microcontact printing
505	8		_a1.3.2.2.2 Three-dimensional printing -- 1.3.2.2.3 Four-dimensional printing -- 1.4 Advanced models of the three-dimensional tumor microenvironment -- 1.4.1 Microfluidics-based models -- 1.4.1.1 Microfluidic-based models of tumors: tumor-on-a-chip -- 1.4.1.2 Drug discovery and screening on-chip -- 1.4.1.3 Reproducing dynamic events on-chip -- 1.4.1.4 Personalized tumor-on-a-chip models -- 1.4.1.5 Manufacturing methods of a tumor-on-a-chip -- 1.4.2 Three-dimensional bioprinted models -- 1.5 Applications of three-dimensional tumor models in cancer therapeutics
505	8		_a1.5.1 Drug discovery, development, and screening -- 1.5.2 Transport and delivery of drugs -- 1.6 Limitations of biomaterials-based three-dimensional tumor models -- 1.7 Future of three-dimensional biomaterials for cancer research -- 1.8 Final remarks and conclusions -- References -- 2 Bioinspired biomaterials to develop cell-rich spherical microtissues for 3D in vitro tumor modeling -- 2.1 Introduction -- 2.2 Human Tumor microenvironment-key hallmarks to mimic in vitro -- 2.3 3D In vitro tumor models-bridging the gap from 2D flat cultures to in vivo -- 2.4 Classes of 3D multicellular tumor models
505	8		_a2.4.1 Scaffold-free cell-rich 3D multicellular tumor spheroids -- 2.4.2 Scaffold-based 3D multicellular tumor models -- 2.4.2.1 Biomaterials for establishing physiomimetic 3D tumor microenvironments -- 2.4.2.1.1 Natural and nature-derived biomaterials for 3D tumor modeling -- Protein-based biomaterials -- Polysaccharide-based biomaterials -- 2.4.2.1.2 Synthetic biomaterials for 3D tumor modeling -- 2.4.2.1.3 Hybrid biomaterials for 3D tumor modeling -- 2.4.3 Generation of spherically structured cell-rich 3D tumor models -- 2.4.3.1 Microparticles for spherically structured 3D tumor models assembly
650		0	_aBiomedical materials. _93868
650		0	_aThree-dimensional imaging in medicine. _968890
650		0	_aTumors _xComputer simulation. _968891
650		2	_aBiomedical and Dental Materials _0(DNLM)D001697 _968432
650		2	_aBiocompatible Materials _0(DNLM)D001672 _95921
650		2	_aImaging, Three-Dimensional _0(DNLM)D021621 _968892
650		6	_aBiomat�eriaux. _0(CaQQLa)201-0025723 _968433
650		6	_aImagerie tridimensionnelle en m�edecine. _0(CaQQLa)201-0210978 _968893
650		6	_aTumeurs _0(CaQQLa)201-0079779 _xSimulation par ordinateur. _0(CaQQLa)201-0379159 _968894
650		7	_aBiomedical materials _2fast _0(OCoLC)fst00832586 _93868
650		7	_aThree-dimensional imaging in medicine _2fast _0(OCoLC)fst01150334 _968890
700	1		_aKundu, S. C. _q(Subhas Chandra) _968895
700	1		_aReis, Rui L. _968896
776	0	8	_iPrint version: _tBiomaterials for 3D tumor modeling. _dAmsterdam, Netherlands : Elsevier, 2020 _z0128181281 _z9780128181287 _w(OCoLC)1135667774
856	4	0	_3ScienceDirect _uhttps://www.sciencedirect.com/science/book/9780128181287
942			_cEBK
999			_c82480 _d82480