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020 _a9783031023910
_9978-3-031-02391-0
024 7 _a10.1007/978-3-031-02391-0
_2doi
050 4 _aQC685-689.55
050 4 _aTA1671-1707
072 7 _aPHJL
_2bicssc
072 7 _aSCI053000
_2bisacsh
072 7 _aPHJL
_2thema
082 0 4 _a621,366
_223
100 1 _aHackbarth, Steffen.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_979018
245 1 0 _aSinglet Oxygen Detection and Imaging
_h[electronic resource] /
_cby Steffen Hackbarth, Michael Pfitzner, Jakob Pohl, Beate Röder.
250 _a1st ed. 2021.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2021.
300 _aVII, 85 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSynthesis Lectures on Materials and Optics,
_x2691-1949
505 0 _aIntroduction -- Detection Introduction -- Indirect Detection of Singlet Molecular Oxygen -- Direct Detection of Singlet Molecular Oxygen -- Time-Resolved Singlet Oxygen Luminescence in Cell Suspensions -- Time-Resolved Singlet Oxygen Luminescence Detection in Microorganisms on Surfaces -- Time-Resolved Singlet Oxygen Luminescence Ex Vivo and In Vivo -- Authors' Biographies .
520 _aSinglet Oxygen, the lowest electronically excited state of molecular oxygen, is highly reactive and involved in many chemical and biological processes. It is one major mediator during photosensitization, which has been used by mankind since ancient times, even though the mechanisms behind it were understood only about half a century ago. The combination of high reactivity and very long natural lifetime allows for direct optical detection of singlet oxygen and its interactions using its characteristic phosphorescence at around 1270 nm. Since this emission is very weak, optical detection was technically very challenging for a long time. Therefore, even today, most laboratories only exploit the high reactivity to observe the interaction with sensor molecules, rather than singlet oxygen emission itself. However, in recent years highly sensitive optical detection was developed, the authors being major contributors. This book is dedicated to the detection of singlet oxygen, discussing possibilities, pitfalls and limits of the various methods with a special focus on time-resolved phosphorescence and the kinetics of singlet oxygen generation and decay including involved and related processes, discussing investigated systems with various complexity from solutions over in vitro to in vivo. The long-standing paradigm that singlet oxygen phosphorescence is a benchmark for detection systems rather than an option for process observation is still ubiquitous and this book hopes to contribute in overcoming this still prevailing bias.
650 0 _aLasers.
_97879
650 0 _aMaterials science.
_95803
650 1 4 _aLaser.
_931624
650 2 4 _aMaterials Science.
_95803
700 1 _aPfitzner, Michael.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_979019
700 1 _aPohl, Jakob.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_979020
700 1 _aRöder, Beate.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_979021
710 2 _aSpringerLink (Online service)
_979022
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031002557
776 0 8 _iPrinted edition:
_z9783031012631
776 0 8 _iPrinted edition:
_z9783031035197
830 0 _aSynthesis Lectures on Materials and Optics,
_x2691-1949
_979023
856 4 0 _uhttps://doi.org/10.1007/978-3-031-02391-0
912 _aZDB-2-SXSC
942 _cEBK
999 _c84699
_d84699