Synthetic nucleic acids as inhibitors of gene expression : mechanisms, applications, and therapeutics implications / edited by Levon Michael Khachigian. - 1 online resource (182 pages)

chapter 1 1 -- chapter 2 Development of Ribozymes as Cancer Therapeutics -- chapter 3 RNA Interference: A Technology Based on an Ancient Gene Silencing Pathway -- chapter 4 RNA-Cleaving DNA Enzymes in Gene Silencing: Room for Improvement? -- chapter 5 Deoxyribozymes and Medical Innovation -- chapter 6 Effect of Modifications on the Intracellular Activity of a DNA Enzyme -- chapter 7 Potential Therapeutic Applications of DNA Enzymes and siRNAs against Viral and Cellular Genes -- chapter 8 Use of DNAzymes for Target Gene Validation -- chapter 9 DNAzymes Targeting Immediate-Early Genes as Inhibitors of Angiogenesis and Restenosis -- chapter 10 Decoy Oligodeoxynucleotides as Viable Pharmaceutical Drugs.

9780429126390

10.1201/9781420037890 doi


Catalytic RNA.
Repressors, Genetic.
Genetic regulation.

QP623.5.C36 / S966 2005

572.8 / S993