Synthetic nucleic acids as inhibitors of gene expression : mechanisms, applications, and therapeutics implications / edited by Levon Michael Khachigian.
Contributor(s): Khachigian, Levon
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BookPublisher: Boca Raton : CRC Press, 2005Description: 1 online resource (182 pages).ISBN: 9780429126390.Subject(s): Catalytic RNA | Repressors, Genetic | Genetic regulationAdditional physical formats: Print version: : No titleDDC classification: 572.8 Online resources: Click here to view. chapter 1 1 -- chapter 2 Development of Ribozymes as Cancer Therapeutics -- chapter 3 RNA Interference: A Technology Based on an Ancient Gene Silencing Pathway -- chapter 4 RNA-Cleaving DNA Enzymes in Gene Silencing: Room for Improvement? -- chapter 5 Deoxyribozymes and Medical Innovation -- chapter 6 Effect of Modifications on the Intracellular Activity of a DNA Enzyme -- chapter 7 Potential Therapeutic Applications of DNA Enzymes and siRNAs against Viral and Cellular Genes -- chapter 8 Use of DNAzymes for Target Gene Validation -- chapter 9 DNAzymes Targeting Immediate-Early Genes as Inhibitors of Angiogenesis and Restenosis -- chapter 10 Decoy Oligodeoxynucleotides as Viable Pharmaceutical Drugs.
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